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Principal Investigators

Gregory Dake Associate Professor

 

Organic: New methods for organic synthesis; metal-mediated or catalyzed processes; tandem reactions; asymmetric catalysis; synthesis and chemistry of biologically active and/or structurally interesting natural products.

 

Our research interests in catalysis involve: (a) the invention and development of new chiral ligands used to support homogeneous catalysis, (b) the invention of new sets of C-C, C-N or C-O bond forming reactions using catalysis, (c) the use of catalytic reactions to build novel molecules of interest to researchers within the field of natural products or the biomedical, pharmaceutical or agrochemical communities and (d) the use of homogeneous catalysis for the breakdown of lignocellulosic biomass . Potential collaborators include individuals or groups interested in any of the above topics or with a specific interest in or need for the synthesis of a target or group of organic molecules.

Dake Group Homepage

Michael D. Fryzuk Professor

 

Inorganic: Synthesis and reactivity of new organometallic and coordination complexes and their use in homogeneous catalysis, asymmetric synthesis and organic synthesis. Activation of small molecules, especially N2.

 


Our catalytic research is concerned with two main areas: (i) activation of small molecules, in particular molecular nitrogen, to generate amines and other nitrogen-containing products; (ii) new catalysts for hydrogenation of esters to alcohols. Potential collaborations include agrochemical and pharmaceutical companies.

Fryzuk Group Homepage

 

Derek P. Gates Associate Professor

 

Inorganic/Polymer: Synthetic Chemistry; the development of new methods to prepare polymers containing inorganic elements; new catalysts and co-catalysts for olefin polymerization

 

Our interests in catalysis include the synthesis of molecular or polymeric phosphorus ligands for transition metal catalysis and the development of recoverable and recyclable catalysts for organic synthesis. Potential collaborators range from pharmaceutical companies interested in green approaches to the synthesis of active pharmaceutical ingredients using catalysis to companies interested in catalysts for the production of polymers.

Gates Group Homepage

John R. Grace

Professor and Canada Research Chair in Clean Energy Processes

Dr. Grace’s primary research interests are concerned with fluidized bed reactors and related multi-phase systems. Fluidized beds are used for a wide variety of chemical and physical purposes, for example in catalytic, gas-solid and three-phase reactors, drying, coating and thermal treatment.

Our catalytic interests are mostly related to modelling of heterogeneous catalytic reactions in gas-fluidized and fixed bed reactors, including such reactions as steam reforming of hydrocarbons, coupled hydrogenation and dehydrogenation reactions, and catalytic oxidation. Potential collaborators include those with activities related to a wide range of energy and hydrocarbon applications.

 

Brian R. James Professor Emeritus

 

Inorganic / Organometallic: Synthesis, and kinetic and mechanistic studies of coordination  and organometallic complexes (usually of platinum metals) relevant to homogeneous catalysis involving activation of small molecules; for example, H2 in hydrogenation / hydrogenolysis reactions; O2 and N2O in oxygenations, CO in carbonylations, utilization of H2S. 

 


Recent and on-going interests include: (a) hydrophosphination reactions, and development of water-soluble phosphines as pulp-bleaching agents; (b) conversion of lignins to valuable aromatics using Ru-oxidation or -hydrogenolysis catalysts; (c) asymmetric hydrogenation of imines to chiral amines using Rh and Ir catalysts; (d) reactions of Pd complexes with H2S; (e) development of Ru complexes as anti-cancer agents; and (f) catalysis using Rh and Ir carbenes. All the projects except (f) have involved collaboration with industrial companies, FPInnovations, or the BC Cancer Agency.

Pierre Kennepohl Associate Professor

Spectroscopy of Intermediates in Biological and Homogeneous Catalysis: Investigations of sulfur-based redox processes and their role in enzymatic catalysis, oxidative stress, and redox signaling. Exploration of transition metal species involved in catalysis (dioxygen binding and oxidation, olefin metathesis, etc.).

The Kennepohl Group uses a combination of spectroscopic and computational methods to probe the electronic structure of catalytically important species. This information is used to provide fundamental new insights into the factors that control reactivity.

Kennepohl Group Homepage

Peter Legzdins Professor

 

Organometallic / Inorganic: Synthetic, structural, bonding, electrochemical, and kinetic studies of transition-metal organometallic compounds and their utilization as specific reactants or selective catalysts in organic or organometallic syntheses leading to chemically important compounds (e.g. the functionalization of hydrocarbons via C-H bond activation). The beneficial physiological properties of metal-nitrosyl complexes.

 

Our catalytic research interests are centred on the transition-metal-mediated activation and functionalization of otherwise inert chemical bonds such as C-H, N-H, and C-C linkages in an atom-economical manner. This chemistry holds the potential to increase considerably the number of synthetic pathways to a broad range of industrially important products beginning with relatively simple starting materials. Potential collaborators range from companies involved in the research and development of hydrocarbons or petrochemicals to firms principally focused on the synthesis of fine chemicals.

Legzdins Group Homepage

Jennifer Love Associate Professor

 

Organic/Organometallic/Coordination Chemistry: Development of new catalytic methods; complex molecule synthesis using newly developed reaction methodology; mechanistic investigation

 


Our catalytic research interest include the study of the reactivity of late transition metal-heteroatom bonds. We use this knowledge to develop new strategies to convert commonly available chemical feedstocks into value-added products. Emphasis on developing highly efficient, low toxicity and low waste methods. Our research spans the traditional boundaries of organic and inorganic chemistry. Potential collaborators include the development of new catalysts, synthesis of chemical building blocks and synthesis of bioactive targets.

Love Group Homepage

Mark MacLachlan Professor

 

Materials/Inorganic/Organic/Supramolecular: Synthesis and characterization; mesoporous materials; conjugated materials; shape-persistent macrocycles; coordination chemistry; supramolecular chemistry; metal-organic frameworks; self-assembled structures; hydrogen storage

 


Our research interests include the development of new porous materials, especially materials that may be relevant to heterogenous catalysis. Our recent work has included the creation of new highly porous metal nitrides and chiral mesoporous silicates. We are interested in creating new solid-state materials for industrially-relevant catalysis.

MacLachlan Group Homepage

Scott McIndoe Associate Professor, Affiliate Member – University of Victoria

Inorganic/Organometallic:  Kinetics and mechanism of homogeneous organometallic catalytic reactions.

Areas of Interest:

We develop real-time mass spectrometric techniques to enable rapid catalyst discovery, mechanism elucidation and reaction optimization. We’re particularly interested in coupling together multiple orthogonal real-time methods of analysis, and are applying these across a wide range of problems in catalysis, including cross-coupling, small molecule activation, polymerization and more.

McIndoe Group Homepage

Parisa Mehrkhodavandi Assistant Professor

 

Organometallic/Inorganic/Catalysis/Polymers: Development of homogeneous catalysts for formation of biodegradable polymers of defined structure; Synthesis and reactivity of novel organometallic complexes

 


We are interested in the development of catalysts for the highly controlled formation of biodegradable polyesters and copolymers. Potential collaborators include pharmaceutical and agrochemical industries interested in hydrophilic, hydrophobic, and amphiphilic biodegradable polymer as well as more downstream industries such as automotive and materials producers interested in controlled micro/macrostructure bulk biodegradable plastics with defined properties.

Mehrkhodavandi Group Homepage

Lisa Rosenberg Associate Professor, Affiliate Member – University of Victoria

Inorganic/Organometallic: Design and synthesis of homogeneous catalysts for silicon and phosphorus chemistry, mechanistic aspects of catalytic E-H activation, structure/property relationships in inorganic polymers

Areas of Interest:

We aim to bring selectivity to main group synthesis through homogeneous catalysis. While organic chemistry is replete with synthetic schemes that rely on catalysis for the efficient construction of structurally complex molecules, this art remains under-exploited in inorganic chemistry. Our research on catalytic P-H and Si-H activation uses in-depth investigation of simple systems to gain the mechanistic understanding required to broaden the scope and utility of these processes in producing valuable molecules and materials. Targets include enantiopure phosphines for asymmetric catalysis, oxidatively robust polysilanes for optical and electronics applications, and precursors to valuable silicone-containing materials, to be produced in tandem with defunctionalization of biomass-derived feedstock chemicals.

Rosenberg Group Page


Glenn Sammis Professor

 

Organic: Investigation of new methods for the syntheses of complex natural products, exploration of proposed biogenetic pathways through biomimetic synthesis, enantioselective synthesis of building blocks for total synthesis.

 


The Sammis group aims to develop innovative synthetic technology for the synthesis of compounds with current biomedical interest. Investigations focus on developing novel bond-construction techniques for which there is currently no viable alternative. The methodology developed in this research program, therefore, has the potential to unlock access to previously unavailable architecturally unique compounds in sufficient quantities for medicinal testing. The Sammis group has particular expertise in the development of radical-based methodologies and is currently focusing on the development of novel asymmetric transformations utilizing catalytic amounts of chiral atom transfer agents.

Sammis Group Homepage

Laurel Schafer Associate Professor

 

Organometallic/Organic: Development of Early Transition Metal and Lanthanide Reagents for Organic Synthesis: i) Preparation of new amidate metal complexes for applications in catalytic hydroamination, C-C bond forming reactions and the synthesis of biodegradable polymers. ii) Fundamental reactivity studies of metal-mediated and catalyzed organic transformations for reagent/catalyst optimization. iii) Development of a class of modular, N,O chelating ligands

 


Our catalytic research interests include the catalytic synthesis of amines and biodegradable polymers using inexpensive early transition metals of low toxicity.  Potential collaborations include research and development of biologically active small molecules for the pharmaceutical and agrochemical industries as well as novel biodegradable polymers for plastics and materials applications.

Schafer Group Homepage

smith
Kevin J. Smith Professor

UBC Chemical and Biological Engineering (CHBE)

Heterogeneous catalyst preparation and characterization; reaction kinetics and mechanisms with a focus on issues related to the Canadian energy scene.

Primary interests are in C1-catalysis, hydrogen and upgrading Canadian oilsands and bio-oils.  Our research aims to develop relationships between catalyst properties, reaction kinetics and mechanisms, to assist in the design of improved catalysts and in the development of new catalytic processes. Our research has focused on (i) Hydroconversion –  residue oil primary upgrading  and hydrotreating; (ii) C1 catalysis – methane and syngas conversion especially to alcohols and (iii) Hydrogen – production and storage.  Potential collaborators include  small and large scale energy companies interested in improving existing catalytic processes or developing new catalysts for specific energy applications.

Martin Tanner Professor

 

Bio-organic: Studies on novel enzyme mechanisms; epimerases and racemases; sugar nucleotide-modifying enzymes; isotope effects; inhibitor design; site-directed mutagenesis.

 


Our catalytic research interests include studies on the mechanisms by which enzymes catalyze biological reactions and on the design of enzyme inhibitors. Ongoing studies involve enzymes that modify peptide, carbohydrate, and alkaloid-based substrates. Potential collaborators include life science researchers, the pharmaceutical industry, and researchers involved in using enzymes as catalysts for the production of fine chemicals.

Tanner Group Homepage

Yan Alexander Wang Associate Professor
Theoretical/Computational: Ab Initio Methods. Orbital-free density-only linear-scaling density-functional methods, Embedding methods for chemical processes on surfaces and interfaces, Developing new kinetic-energy, exchange-correlation, and total energy density functionals, Mathematical properties of density functionals and mathematical foundation of density-functional theory, Molecular simulation and modeling of nanosystems and biological systems


Our catalytic research interests include computational modeling of catalytic reactions and theoretical understanding of reaction mechanisms, with special emphasis on novel catalytic systems at nanoscale. Potential collaborations include research and development of better catalysts based on microscopic understanding of existing catalytic systems.

Wang Group Homepage

David Wilkinson  Professor and Canada Research Chair

UBC Chemical and Biological Engineering (CHBE)

The overall scope of the program is the research and development of electrochemical power sources, advanced electrolysis, and processes to create clean and sustainable energy particularly related to electrochemistry and electrochemical engineering. Dr. Wilkinson has research interests in the areas of electrode kinetics, electro-catalysis, electro-synthesis, electrochemical cell design and architecture, new materials and associated processes, new analytical and diagnostic techniques, sensor technology, fuel cell and battery systems, electrochemical treatment of impurities, alternative electrochemical fuels and reactant modification, hydrogen production and storage. Recently his research has expanded to include some aspects of solar research particularly those coupled with electrochemistry and the purification of water.

 

Our catalytic research interests include the development, design and characterization of electrochemical and photochemical catalysts for energy related applications and their incorporation into  electrodes and reactors. Potential collaborations include research and development of catalysts, materials and device design for the fuel cell and advanced battery industries as well as for water treatment and processes to create clean and sustainable energy.

Stephen G. Withers Professor

 

Joint appointment with: BiochemistryBioorganic: Enzyme mechanisms; glycosyl transfer mechanisms; carbohydrate chemistry; fluorinated sugars; hydrogen bonding and specificity; applications of 31P and 19F-NMR to enzymology; biological electrospray ionisation mass spectrometry; amylases and cellulases; mutagenesis; directed evolution; glycosyl transferases; polysaccharide lyases

 


Our research interests centre around enzymes as catalysts, both in understanding how they work and in engineering them to enhance their functions. Of particular interest to us are enzymes that synthesise and degrade sugar-containing polymers. We are actively working in the area of biofuels as well as development of processes for synthesis of oligosaccharides and glycolipids, and have potential to expand our collaborations in these areas.

Withers Group Homepage

Michael O. Wolf Professor

 

Inorganic/ Materials/Polymers: Synthesis of metal-containing conjugated materials; organic and polymer light-emitting devices; molecular electronics; electrochemistry and scanning probe microscopy of self-assembled monolayers; modified electrode surfaces; materials for chemical sensing.

 


Our catalytic research interests include the preparation of nanomaterials including metal nanoparticles, oxide nanocrystals and conducting polymer/nanomaterial composites for application in water splitting, hydrocarbon oxidation and solar energy harvesting. Potential collaborators include partners interested in energy related catalysis, solar energy harvesting, and electrocatalysis.

Wolf Group Homepage

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UBC 3D
Dr. Laurel Schafer
Director,
Vancouver, BC, Canada
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